Literature on Psoriatic Arthritis

Related ArticlesClinical evaluation and comparison of different criteria for classification in Turkish patients with psoriatic arthritis.

Rheumatol Int. 2008 Aug;28(10):959-64

Authors: Gunal EK, Kamali S, Gul A, Ocal L, Konice M, Aral O, Inanc M

Several criteria are being used for the classification of psoriatic arthritis (PsA) and there is a lack of consensus about PsA as a separate entity. Our aim is to investigate the clinical features of our patients with a clinical diagnosis of PsA, compare the sensitivities of different classification criteria and agreement between the criteria. In this study 86 PsA patients were investigated (48 female, mean age 44). Moll and Wright criteria were fulfilled by 91%, Vasey and Espinoza criteria by 94% and modified European SpA study group criteria by 59%, classification of PsA study group criteria by 86%, modified McGonagle criteria by 96%, Fournié et al. criteria by 84%, and Gladman criteria by 95%. Significant agreement was present between criteria but generally kappa values were less than 0.5. The pattern of PsA can differ with time and the implementation of the available classification criteria showed considerable differences.

PMID: 18317769 [PubMed - indexed for MEDLINE]

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Related ArticlesCoexistence of five autoimmune diseases: diagnostic and therapeutic difficulties.

Rheumatol Int. 2008 Jul;28(9):919-23

Authors: Wielosz E, Majdan M, Zychowska I, Jeleniewicz R

We report the case of coexistence of five autoimmune diseases in a 36-year-old woman, who initially developed psoriasis. Several years later, the patient was diagnosed with a mixed connective tissue disease and primary biliary cirrhosis (PBC). On admission to the Department of Rheumatology and Connective Tissue Diseases, the patient fulfilled classification criteria of an overlap syndrome systemic lupus erythematosus (SLE) with secondary antiphospholipid syndrome/systemic sclerosis (SSc)/Sjogren’s syndrome (SS) with coexisting PBC and psoriasis. The SLE symptoms included discoid lupus erythematosus, arthritis, pancytopenia, antinuclear antibodies and anticardiolipin antibodies. Moreover, the patient met the criteria of antiphospholipid syndrome diagnosed based on preterm delivery before week 34, and high values of anticardiolipin antibodies were found at repeated determinations. The SSc symptoms included sclerodactyly, pulmonary fibrosis with pulmonary hypertension and esophageal dysfunction. The SS syndrome involved xerostomia, xerophthalmia, the positive Schirmer’s test and presence of anti-SS antibodies. The literature reports overlap syndromes in various combinations; however, the coexistence of five autoimmune diseases is extremely rare.

PMID: 18320193 [PubMed - indexed for MEDLINE]

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Related ArticlesPolymorphism of the prolactin extrapituitary promoter in psoriatic arthritis.

Rheumatol Int. 2007 Sep;27(11):1095-6

Authors: Stolfa J, Fojtíková M, Cejková P, Cerná M, Sedová L, Dostál C

PMID: 17564716 [PubMed - in process]

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Related ArticlesFrequency of rheumatic diseases in patients with autoimmune thyroid disease.

Rheumatol Int. 2006 Nov 11;

Authors: Soy M, Guldiken S, Arikan E, Altun BU, Tugrul A

We aimed to investigate the frequency of rheumatic diseases in patients suffering from autoimmune thyroid diseases (ATD). Sixty-five patients (56 F, 9 M), who were followed by diagnosis of ATD, were questioned and examined for the presence of rheumatic disease. Basic laboratory tests and antithyroid antibodies, antinuclear antibody and rheumatoid factor (RF) levels were also measured by appropriate methods. Various rheumatic diseases were detected in 40 (62%) of patients with ATD. The most frequent rheumatic conditions were fibromyalgia, recurrent aphthous stomatitis, osteoarthritis, keratoconjunctivitis sicca and xerostomia and carpal tunnel syndrome which were detected in 20 (31%), 13 (20%), 10 (15%), 9 (14%) and 8 (12%) of patients, respectively. Autoimmune diseases, except Sjogren’s syndrome, which were detected in ten patients with ATD, are as follows-vitiligo: two; autoimmune hepatitis: two; oral lichen planus: one, ulcerative colitis: one, inflammatory arthritis in four patients (two of them had rheumatoid arthritis, one had psoriasis and psoriatic arthritis and one had mixed collagen tissue disease). RF was positive in two patients, one of them had rheumatoid arthritis and FANA was positive in six (9%) patients; all of them had hypothyroidism. The frequency of rheumatic diseases seems to be higher in patients suffering from ATD. Initial evaluation and a regular checking for rheumatic diseases in patients suffering from ATD were recommended.

PMID: 17102943 [PubMed - as supplied by publisher]

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MRI in psoriatic arthritis with hand and foot involvement.

Rheumatol Int. 2006 Oct 7;

Authors: Ghanem N, Uhl M, Pache G, Bley T, Walker UA, Langer M

Evaluation of MRI-findings in patients with involvement of psoriatic arthritis (PsA) in small joints in hands and feet. Twenty-five patients with symptomatic joint involvement were studied by MRI. All patients were found to be positive for one or more imaging criteria. Soft tissue oedema was identified in 22/25 (88%) patients. Joint effusion was observed in 23/25 (92%) patients, whereas bone erosion was seen in 20/25 (80%) patients. Bone marrow oedema was evident in 21/25 (84%) cases. In 12/25 (48%) cases, bone proliferation was noted. Tendon sheath effusion was present in 17/25 (68%) patients. Contrast enhancement of the synovia was detected in all patients (n = 25) (100%), whereas adjacent periost was enhanced in 22/25 (88%) and epiphysial bone marrow in 18/25 (72%) patients. MRI allows the assessment of PsA-alterations of soft tissue, cartilage, bone, bone marrow, and adjacent tendon sheath in patients with hand and foot involvement.

PMID: 17028861 [PubMed - as supplied by publisher]

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Purpura and serum mixed cryoglobulinemia in psoriatic arthritis.

Rheumatol Int. 2006 Aug 10;

Authors: Palazzi C, D’Amico E, Pennese E, Petricca A, Olivieri I

We here firstly describe the case of a psoriatic arthritis associated with cutaneous purpura and lower limbs weakness. The presence of type III mixed cryoglobulinemia in serum was the only possible detected cause. Discrepancies with the hepatitis C virus-related mixed cryoglobulinemia picture are discussed.

PMID: 16900374 [PubMed - as supplied by publisher]

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Related ArticlesPurpura and serum mixed cryoglobulinemia in psoriatic arthritis.

Rheumatol Int. 2006 Aug 10;

Authors: Palazzi C, D’Amico E, Pennese E, Petricca A, Olivieri I

We here firstly describe the case of a psoriatic arthritis associated with cutaneous purpura and lower limbs weakness. The presence of type III mixed cryoglobulinemia in serum was the only possible detected cause. Discrepancies with the hepatitis C virus-related mixed cryoglobulinemia picture are discussed.

PMID: 16900374 [PubMed - as supplied by publisher]

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Psoriasis onset during infliximab treatment: description of two cases.

Rheumatol Int. 2006 Jun 1;

Authors: Volpe A, Caramaschi P, Carletto A, Pieropan S, Bambara LM, Biasi D

The authors describe two patients with no personal or family history of psoriasis who developed psoriatic lesions during infliximab treatment: a woman affected by seronegative rheumatoid arthritis and a man affected by ankylosing spondylitis.

PMID: 16738903 [PubMed - as supplied by publisher]

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Related ArticlesMagnetic resonance imaging guided corticosteroid injection of sacroiliac joints in patients with spondylarthropathy. Are multiple injections more beneficial?

Rheumatol Int. 2006 Mar;26(5):396-400

Authors: Günaydin I, Pereira PL, Fritz J, König C, Kötter I

Efficacy of a second magnetic resonance (MR) imaging guided corticosteroid injection of inflamed sacroiliac joints (SIJ) in patients with spondylarthropathy. Thirty-one patients received 50 injections in an outpatient basis. Fifteen of 31 patients who relapsed or were non-responders received a second injection. All had MR guided injection of 40 mg triamcinolone acetonide into SIJ using an open 0.2 Tesla unit. Twenty of 31 patients after the first injection, and 9 of 15 patients after the second injection reported subjective improvement, which lasted for a mean of 8.7+/-10.9 and 16.1+/-15.8 months for each group. Subchondral bone marrow edema resolved in 15 of 20 patients who reported subjective improvement, after the first injection. No complications occurred. MR guided steroid injection of SIJ is effective and safe. Since there is no exposure to radiation it could be performed many times. Repeated injections seem to be beneficial for primary non-responders and patients who relapsed.

PMID: 16010559 [PubMed - as supplied by publisher]

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Related ArticlesAnalgesic and disease modifying effects of interferential current in psoriatic arthritis.

Rheumatol Int. 2006 Jan 24;:1-4

Authors: Walker UA, Uhl M, Weiner SM, Warnatz K, Lange-Nolde A, Dertinger H, Peter HH, Jurenz SA

Interferential current (IFC) was suggested to improve the skin manifestations of psoriasis vulgaris, possibly by enhancing the intracellular concentration of cyclic AMP. We assessed the efficacy of IFC on psoriatic arthritis (PsA). Nine consecutive patients were analyzed at baseline and after 16 weeks of IFC therapy. Bipolar IFC was applied twice daily to hands, feet plus all affected joints. IFC improved SF-36 assessed body pain, but not other SF-36 subscales. Morning stiffness, tender joint counts, and physician assessed disease activity improved. In contrast, visual analogue scale assessed pain, CRP and ESR measurements were unchanged. MRI of the most affected hand or foot documented a tendency towards worsened tendinitis, soft tissue swelling, and new joint space narrowing and erosions. Bone scintigraphy showed a trend towards deterioration. New joints became inflamed within treated sites. Thus IFC has analgesic effects in PsA, but does not have a satisfactory disease modifying effect.

PMID: 16432686 [PubMed - as supplied by publisher]

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